Acne starts during puberty when your body signals your sebum glands to secrete an oily element that when on the surface of the skin it lubricates it and shields your skin from infection by microbes that thrive there permanently. If sebum does not outflow swiftly through the sebum canals to the surface it produces several skin injuries that trigger an inflammatory reaction and the sebum accumulated there becomes a rich feeding ground for the proliferation of microbes.

Such infections place heavy demands upon the skin's components. Areas with continued acne infections caused by severe or moderate acne frequently develop deficiencies of basic ingredients, impairing the skin's capability to defend itself and heal efficiently.

Acne infections destroy collagen and elastin fibers, interrupt the microvascular network and damage and kill cells. When healing happens, normally after a long time if an adequate acne treatment has not be applied, a scar is left in the skin. The normal functional tissue (skin) is replaced by connective tissue (scar).

Natural Ingredient Treats Acne

Nowadays, antibiotics like penicillin are not powerful as they were before to deal with bacteria. What really happens is that the bacteria, having a high rate of mutation, ends up changing one or more of its enzymes that are used to destroy the union between a target protein and the antibiotic. As a result, the antibiotic does not have effect.

But this system fails when the attacker punches holes in the cell membrane, as peptide antibiotics do. To defend itself, the bacterium would have to modify the entire structure of the cell membrane. And to change the structure of a membrane would imply modifying most of the enzymes that are responsible for making the complex membrane in the first place.

Peptide antibiotics react within minutes helping treat acne instantly. Part of the reason for this quick response is how the peptide works on the cell membrane. But to destroy a cell, the peptide must also quickly find the bacterial membrane. How does this occur? The answer lies in the construction of the cellular membrane.

The plasma membrane of eukaryotic cells is much different than the membrane of a prokaryotic cell. Eukaryotic cell membranes are made of a phospholipid bilayer and cholesterol. Consequently, these membranes have a low negative electrical charge. On the other hand, a bacterial membrane is composed by fats and sugars. This difference in composition means that bacteria have a high negative electrical charge that quickly attracts the peptide antibiotics.

Peptide antibiotics are effective. In a clinical trial for the treatment of meningitis, a sickness that affects 3,000 children a year, a peptide antibiotic not only destroyed the bacterium which mades the toxin, but it also bound to the toxin avoiding the damage the endotoxin causes. But bringing a new drug to clinical trial is time consuming and expensive. It takes $300 million to bring a drug to market. This cost covers every thing from finding, identification, production and clinical trials. This process may also take ten or more years to accomplish.